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parnew

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After reading many posts about this problem in our dogs I think it needs to brought to the attention of K9ers that not only the breeding closely can cause these heart problems and we need to understand that there is many forms of these heart conditions that many people are putting under the one banner, over the next few days I will share some of my own research with you, for those that don't know me I have been working in a Cardiac Cath Lab for 4 years and have spoke at length with cardiologists about some of the causes " VENTRICULAR ECTOPY " and other conditions. It was explained to me that whippets and athletes have enlarged hearts because of there sprinting ability and fitness which makes the walls of the heart thicker and the left ventricle larger, this causing problems later in life. Please find some of the things I've found to help explain most of the problems in our breed.

ECHOCARDIOGRAPHIC REFERENCE VALUES IN WHIPPETS

All work was carried out at the Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.

A limited part of this work was presented as a poster-presentation at the ECVIM Congress 2004, Barcelona, Spain.

Copyright © Copyright 2007 by the American College of Veterinary Radiology

KEYWORDS

ABSTRACT

The aim of the study was to establish reference echocardiographic values for whippets, to compare these values with previously published reference values for the general dog population, and to determine whether there is an influence of gender and breeding lines on echocardiographic measurements. Echocardiographic parameters from 105 apparently healthy whippets without cardiac symptoms were used to establish reference values for the breed and to compare these values with two previously reported reference ranges. The coefficients of the allometric equation Y=aMb, useful to reconstruct normal M-mode and two-dimensional average values for whippets of varying weights, were calculated, as well as the lower and upper limits of the 95% prediction interval. First, we found that whippets have a significantly larger left ventricular diameter, increased left ventricular wall, and interventricular septum thickness than expected, in diastole as well as in systole. Fractional shortening was significantly lower than the reference value. Second, comparing males and females, taking body weight differences into account, females had a significantly larger left ventricular diameter in diastole and systole. Minor differences were found between racing and show pedigree dogs. In conclusion, the results of this study confirm that breed-specific reference values are needed in echocardiography. In whippets, the values found in this study can be used as references in order to avoid overinterpretation of cardiac dilation, hypertrophy, and/or decreased contractility in these dogs.

Ectopic heartbeat

Definition

Ectopic heartbeat is an irregularity of the heart rate and heart rhythm involving extra or skipped heartbeats.

Alternative Names

PVB (premature ventricular beat); Premature contraction; Premature beats; PVC (premature ventricular contraction); Extrasystole

Causes

Ectopic heartbeats are an arrhythmia involving small variations in an otherwise normal heartbeat. In many cases, they may occur without obvious cause and be benign .

Other times, however, they are associated with electrolyte abnormalities in the blood which should be corrected. They can also be associated with ischemia, or local reduction in blood supply to the heart. In addition, ectopic beats may be caused or made worse by excessive smoking, alcohol consumption , caffeine , certain medications, and some illicit drugs.

Ectopic beats are rare in children other than those with congenital heart disease . The majority of extra heartbeats in children are PAC's (premature atrial contractions), which are almost always benign .

In adults , ectopic beats can occur more commonly, and underlying reversible reasons should be investigated even if it turns out that no treatment is ultimately needed.

Symptoms

* Sensation of feeling heart beat ( palpitations )

* Sensation of stopped or skipped beats

Note: In many cases, the person may have no symptoms.

Exams and Tests

A physical examination may show an occasional irregularity, but if the ectopic beats do not occur frequently, they may not be detectable on physical exam. Blood pressure is usually normal.

The following tests may be used to diagnosis an ectopic heartbeat:

* ECG

* Continuous ambulatory cardiac monitoring (Holter monitor)

* Echocardiogram

* Coronary angiography

Treatment

Often ectopic heartbeats do not require treatment. The condition is treated if symptoms are severe or if extra beats are very frequent.

An underlying cause, if discovered, may also require treatment.

Outlook (Prognosis)

Ectopic heartbeats are generally benign , requiring no treatment. Occasionally, they may indicate an increased risk for other cardiac arrhythmias.

Possible Complications

* Ventricular tachycardia (occasionally)

* Other arrhythmias (occasionally)
 
Arrhythmias

Definition

An arrhythmia is any disorder of your heart rate or heart rhythm, such as beating too fast (tachycardia), too slow (bradycardia), or irregularly.

Alternative Names

Dysrhythmias; Abnormal heart rhythms; Bradycardia; Tachycardia

Causes

Normally, the 4 chambers of the heart (2 atria and 2 ventricles) contract in a very specific, coordinated manner.

The electrical impulse that signals your heart to contract in a synchronized manner begins in the sinoatrial node (SA node), which is your heart's natural pacemaker.

The signal leaves the SA node and travels through the 2 upper chambers (atria). Then the signal passes through another node (the AV node), and finally, through the lower chambers (ventricles). This path enables the chambers to contract in a coordinated fashion.

Problems can occur anywhere along this conduction system, causing various arrhythmias . Examples include:

* Supraventricular tachycardia - a fast heart rate that originates in the upper chambers (atria). The most common are atrial fibrillation or flutter , and atrioventricular nodal reentry tachycardia .

* Ventricular tachycardia - a fast heart rate that originates in the lower chambers (ventricles).

* Bradycardia - a slow heart rate due to problems with the SA node's pacemaker ability, or some interruption in conduction through the natural electrical pathways of the heart.

The risks of getting a tachycardia or bradycardia varies greatly, depending on the condition of your heart, prior heart attack, blood chemistry imbalances, or endocrine abnormalities.

Arrhythmias may also be caused by some substances or drugs, including beta blockers, psychotropics, sympathomimetics, caffeine , amphetamines, and cocaine. Sometimes antiarrhythmic medications -- prescribed to treat one type of arrhythmia -- can actually cause another type of arrhythmia.

Some types of arrhythmias may be life-threatening if not promptly and properly treated.

Symptoms

* Fast or slow heart beat ( palpitations )

* Skipping beats

* Fainting

* Light-headedness , dizziness

* Chest pain

* Shortness of breath

* Skipping beats - changes in the pattern of the pulse

* Paleness

* Sweating

* Cardiac arrest

The person may not have symptoms.

Exams and Tests

A doctor will listen to your heart with a stethoscope and feel your pulse. Your blood pressure may be low or normal.

The following tests may be performed to identify arrhythmias:

* ECG

* Ambulatory cardiac monitoring with a Holter monitor (used for 24 hours) or loop recorder (worn for 2 weeks or longer)

* Echocardiogram

* Electrophysiology study (EPS)

* Coronary angiography

If an arrhythmia is detected, various tests may be done to confirm or rule out suspected causes. EPS testing may be performed to locate the origin of the arrhythmia and determine the best treatment, especially if a pacemaker implantation or catheter ablation procedure is being considered.

Treatment

When an arrhythmia is serious, urgent treatment may be required to restore a normal rhythm. This may include intravenous medications, electrical "shock" therapy (defibrillation or cardioversion), or implanting a temporary pacemaker to interrupt the arrhythmia.

Supraventricular arrhythmias may be treated with anti-arrhythmic drugs. However, most supraventricular arrhythmias can be treated and cured with radiofrequency ablation, eliminating the need for lifelong drug therapy.

Increasingly, most ventricular tachycardias are treated with an implantable cardioverter-defibrillator (ICD). As soon as arrhythmia begins, the ICD sends a shock to terminate it, or a burst of pacing activity to override it.

Bradycardias that cause symptoms can be treated by implanting a permanent pacemaker .

Outlook (Prognosis)

The outcome is dependent on several factors:

* The kind of arrhythmia -- whether it is supraventricular tachycardia , or a more dangerous arrhythmia such as ventricular tachycardia or ventricular fibrillation , which are potentially fatal

* The overall pumping ability of the heart

* The underlying disease and its ability to be treated

With bradycardias treated with a permanent pacemaker , the outlook is usually good.

Possible Complications

* Angina (chest pain caused by imbalance of supply and demand for oxygen in the heart muscle)

* Heart attack

* Heart failure

* Stroke

* Sudden death
 
Ventricular fibrillation

Alternative Names

VF; Fibrillation - ventricular

Definition

Ventricular fibrillation (VF) is a severely abnormal heart rhythm ( arrhythmia ) that causes death unless immediately treated. VF is responsible for 75 - 85% of sudden deaths in persons with heart problems.

Causes

To pump blood out to the body, all areas of the heart normally squeeze (contract) at the same time. The heart’s upper chambers (the atria) contract before the heart’s bottom two chambers (ventricles). During VF , however, the contractions become disorganized.

The most common cause of VF is a heart attack, but VF can occur whenever the heart does not get enough oxygen or if a person has other heart disorders.

Conditions that can lead to VF include:

* Congenital heart disease

* Electrocution accidents or injury to the heart

* Heart attack

* Heart muscle disease , including cardiomyopathies

* Heart surgery

* Ischemia (lack of oxygen to the heart muscle because of narrowed coronary arteries or shock)

While most people suffering from VF have no previous history of heart disease, many have risk factors for cardiovascular disease, such as smoking, hypertension , and diabetes.

Symptoms

A person who has a VF episode will suddenly collapse or become unconscious, because the brain and muscles have stopped receiving blood from the heart.

The following symptoms may occur within 1 hour before the collapse:

* Chest pain

* Dizziness

* Nausea

* Rapid heart beat

* Shortness of breath
 
Whippets (and greyhounds) have arrythmia's at rest. Every racing dog I have owned had an irregular heart rate at rest (tachycardic heart rate when excercised/galloped with no arrythymia). This is normal for them. They have HUGE hearts compared to other breeds.

The thing that bothered me is that the lady, who posted on this forum, had a whippet who died before she was 2 years of age. This is not normal, despite the difference in whippet heart anatomy/physiology.

I've got 2x 10 year old greyhounds down the back yard, still going strong with their athletic hearts. Our other greyhound lived till he was 16 (almost 17).

The rub of all this is how can you tell if it's genetic or not? You can't. Testing your breeding stock is a good start. I'd only go to a cardiac specialist though.

edit for typos because I can't spell for crackers ;)
 
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To find out what kind of problem our dogs may have we can have an ECG or an Echocardiogram done, this will tell us a lot about the function, size, volume of blood pumped, valves and the heart rhythm, but two healthy dogs with no known cardiac problems can produce a dog with problems, so until we can find out what gene or genes are the ones causing the problems it will be hard to stamp out. Not breeding to close is a start but we will never be total remove this as there are other causes other that line breeding.
 
GotWhippet? said:
Whippets (and greyhounds) have arrythmia's at rest. Every racing dog I have owned had an irregular heart rate at rest (tachycardic heart rate when excercised/galloped with no arrythymia). This is normal for them. They have HUGE hearts compared to other breeds.
The thing that bothered me is that the lady, who posted on this forum, had a whippet who died before she was 2 years of age. This is not normal, despite the difference in whippet heart anatomy/pysiology.

I've got 2x 10 year old greyhounds down the back yard, still going strong with their athletic hearts. Our other greyhound lived till he was 16 (almost 17).

The rub of all this is how can you tell if it's genetic or not? You can't. Testing your breeding stock is a good start. I'd only go to a cardiac specialist though.


So true, it is so sad for Gail to have lost her little girl but with heart conditions they can strike at any time, just this week we had a 16 year old girl in the lab that has a fatal heart condition but with treatment she will make it.

Arrythmia's are fine and 70% of people between 40 and 60 have this, the problems start when the heart goes into VT or VF and no cardiac output and they have a heart attack the heart stops beating and we know the rest.
 
Also posted o TWF

I have been asked by 'Wendye Slatyer' ( Calahorra Whippets ) to give the facts about 'Rose' ( Calahorra Neva Endnstory ) ...

As soon as it was discovered that there was a problem , the Bitch was removed from any breeding program - as was all her progeny, most of which have already been de-sexed.

Due to the usual longevity of these lines , most living well into double figures , the results were both tragic and unexpected by all concerned.

Rhonda Tait ( Rose's Owner ) has given the details of the two litters affected ....

Litter 1

Nevedith Lfa Limelight x Calahorra Neva Endnstory - This litter has two whippets out of a litter of six with a problem that I am aware of. Pagan who died at 2 years of age with a heart arrhythmia (cardiac ectopy) and LJ (now called Pepe) who has autoimmune arthritis (who as far as I know is alive but when I last heard his prognosis was not good).

Litter 2

Calahorra Magic Dragon x Calahorra Neva Endnstory - This litter has two whippets out of a litter of seven with a problem that I am aware of. Clarence who died from heart failure at 18 months while being administered anaesthetic (isoflurine gas) and Hopper who has a severe case of cardiomyopathy (sic) who is still alive and on medication for his condition.

The pedigree's of the dogs mentioned can all be found on the Whippet Archives.

Thankyou to Wendye & Rhonda for your openness

Libby - Arjuna Whippets
 
I have just posted this in Patsy's thread but I thought it of relevance to this thread also.

This is interesting. It is in relation to the work being carried out on EBV's (Estimated Breeding Values) by The Animal Health Trust. It's about half way down the page.

http://www.thecavalierclub.co.uk/start.html

Jenny
 
Thanks Libby, I know these lines well, we have them on our data base.

We have some of Wendye's lines down here ( a niece of Calahorra Neva Endnstory ) and the oldest of those are two in March 2009 and so far nothing has turned up with any heart trouble but I will keep an eye out. We have breed two litters from a son of our Calahorra bitch and no know heart problems there at this stage so fingers crossed that it may have missed us for now but will watch them closely.

Does this mean that all the dogs in this pedigree and other dogs with some of this breeding need to be taken out of the breeding program.
 
Hopefully this was an isolated problem ... as Wendye said , they never had a problem previously ....

It may just be that the dog & bitch were just a bad match ... Genetically ??

As I've said in a post elsewhere .. until such time as we have a definitive test that guarantees 100% that stock is clear ... we are all just trying our best , test yes , rely on that test ... Who Knows !!!!!!

The best thing is - not to throw stones etc etc .... But for everyone to be honest and do their best to eradicate any problems ...

The trouble with 'Genetics' is .... They are genetic ... you never know when they will show their ugly heads ..... Until the Boffins get the right tests , available to everyone , we will have to rely on our own abilities and knowledge .....

Good Luck

Libby
 
Dotti said:
Hopefully this was an isolated problem ... as Wendye said , they never had a problem previously ....
It may just be that the dog & bitch were just a bad match  ...  Genetically ??

As I've said in a post elsewhere .. until such time as we have a definitive test that guarantees 100% that stock is clear ... we are all just trying our best , test yes , rely on that test ... Who Knows !!!!!!

The best thing is - not to throw stones etc etc .... But for everyone to be honest and do their best to eradicate any problems ...

The trouble with 'Genetics' is .... They are genetic ... you never know when they will show their ugly heads  ..... Until the Boffins get the right tests , available to everyone , we will have to rely on our own abilities and knowledge  .....

Good Luck

Libby


True Libby....... and I agree we must be up front and all work together to cut down on the number of dogs with these types on problems, its not fair on the dogs or the owners when they die so young :thumbsup:
 
Dotti said:
Hopefully this was an isolated problem ... as Wendye said , they never had a problem previously ....
It may just be that the dog & bitch were just a bad match  ...  Genetically ??

As I've said in a post elsewhere .. until such time as we have a definitive test that guarantees 100% that stock is clear ... we are all just trying our best , test yes , rely on that test ... Who Knows !!!!!!

The best thing is - not to throw stones etc etc .... But for everyone to be honest and do their best to eradicate any problems ...

The trouble with 'Genetics' is .... They are genetic ... you never know when they will show their ugly heads  ..... Until the Boffins get the right tests , available to everyone , we will have to rely on our own abilities and knowledge  .....

Good Luck

Libby

Interesting that the sires were very different in breeding. I think we need to remember that I am sure there are other whippets around from completely different lines that have had problems - so please lets not 'tar' these

Completely agree Libby - we just need to try our best :D

Thanks very much Parnew for all the interesting info :thumbsup:
 
Dotti said:
Also posted o TWF


I have been asked by 'Wendye Slatyer' ( Calahorra Whippets ) to give the facts about 'Rose' ( Calahorra Neva Endnstory ) ...

As soon as it was discovered that there was a problem , the Bitch was removed from any breeding program - as was all her progeny, most of which have already been de-sexed.

Due to the usual longevity of these lines , most living well into double figures , the results were both tragic and unexpected by all concerned.

Rhonda Tait ( Rose's Owner ) has given the details of the two litters affected ....

Litter 1

Nevedith Lfa Limelight x Calahorra Neva Endnstory - This litter has two whippets out of a litter of six with a problem that I am aware of. Pagan who died at 2 years of age with a heart arrhythmia (cardiac ectopy) and LJ (now called Pepe) who has autoimmune arthritis (who as far as I know is alive but when I last heard his prognosis was not good).

Litter 2

Calahorra Magic Dragon x Calahorra Neva Endnstory - This litter has two whippets out of a litter of seven with a problem that I am aware of. Clarence who died from heart failure at 18 months while being administered anaesthetic (isoflurine gas) and Hopper who has a severe case of cardiomyopathy (sic) who is still alive and on medication for his condition.

The pedigree's of the dogs mentioned can all be found on the Whippet Archives.

Thankyou to Wendye & Rhonda for your openness

Libby - Arjuna Whippets

How good to witness such honesty from the owner of Calahorra Neva Endnstory, following what must be very distressing events.

I hope this will encourage other breeders/owners to be equally honest. However it must be rememberd that health problems often cannot be forseen, and therefore breeders must not be blamed for health problems which do arise, unless they could reasonably have been forseen.

I have a genetically inherited health condition but I am not blaming my parents.

Pauline
 
dont you think this should be on general dog related discussion as it is about whippets and greyhounds,others not just show people will find this interesting :thumbsup: but again as its posted on showing it seems like we the show people are getting the blame again :(
 
I do not think it is about anyone getting the blame, but I do agree that this would be best placed where there is a greater chance of everyone seeing it :thumbsup:

Thanks for the info Griff, I will read it again properly later, when I'm not at work! :- "
 
parnew said:
Does this mean that all the dogs in this pedigree and other dogs with some of this breeding need to be taken out of the breeding program.
I wouldn't take them out of a breeding program. Taking out a whippet related to the bitch mentioned is a hell of alot of whippets. I'd be testing them though.
 
I would just like to say to everybody .... you cannot blame anyone or any kennel for the problems that are now occuring .... We have all played our part ....

Even if you don't breed , how many times have you wanted a puppy of a certain colour or from a particular dog or bitch ...

We are all responsible and therfore we all have a responsability to make changes...

Don't throw stones !!!! Work together and try to eradicte the problems , we do , after all want the same thing ... ??

Healthy , Happy Whippets that will be lying on our Sofa's for many years to come ...

Libby
 
Dotti said:
I would just like to say to everybody .... you cannot blame anyone or any kennel for the problems that are now occuring .... We have all played our part ....
Even if you don't breed , how many times have you wanted a puppy of a certain colour or from a particular dog or bitch ...

We are all responsible and therfore we all have a responsability to make changes...

Don't throw stones !!!! Work together and try to eradicte the problems , we do , after all want the same thing ... ??

Healthy , Happy Whippets that will be lying on our Sofa's for many years to come ...

Libby

Don't be ridiculous,

No one is blaming anyone for deliberately doing a fatal mating. The dogs breeding was mentioned, as it should be. For someone to have the guts and say the dogs breeding (and many fluff talkers on these forums don't do that) is a step forward in awareness.
 
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GotWhippet? said:
Dotti said:
I would just like to say to everybody .... you cannot blame anyone or any kennel for the problems that are now occuring .... We have all played our part ....
Even if you don't breed , how many times have you wanted a puppy of a certain colour or from a particular dog or bitch ...

We are all responsible and therfore we all have a responsability to make changes...

Don't throw stones !!!! Work together and try to eradicte the problems , we do , after all want the same thing ... ??

Healthy , Happy Whippets that will be lying on our Sofa's for many years to come ...

Libby

Don't be ridiculous,

No one is blaming anyone for deliberately doing a fatal mating. The dogs breeding was mentioned, as it should be. For someone to have the guts and say the dogs breeding (and many fluff talkers on these forums don't do that) is a step forward in awareness.

I don't think Libby has said that, and no one breeds to cause problems but when problems arise they will have to be dealt with and hope everyone is honest.
 
patsy said:
GotWhippet? said:
Dotti said:
I would just like to say to everybody .... you cannot blame anyone or any kennel for the problems that are now occuring .... We have all played our part ....
Even if you don't breed , how many times have you wanted a puppy of a certain colour or from a particular dog or bitch ...

We are all responsible and therfore we all have a responsability to make changes...

Don't throw stones !!!! Work together and try to eradicte the problems , we do , after all want the same thing ... ??

Healthy , Happy Whippets that will be lying on our Sofa's for many years to come ...

Libby

Don't be ridiculous,

No one is blaming anyone for deliberately doing a fatal mating. The dogs breeding was mentioned, as it should be. For someone to have the guts and say the dogs breeding (and many fluff talkers on these forums don't do that) is a step forward in awareness.

I don't think Libby has said that, and no one breeds to cause problems but when problems arise they will have to be dealt with and hope everyone is honest.


most whippets are clear from any problems

(edited to repair quotes)
 
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